Clinical Data

Otinova® Ear Spray

Summary

Otinova Ear Spray is an aluminium acetate solution. Multiple studies have been conducted on aluminium acetate, particularly in relation to ear infections, and you can find the details of many of these below.

Clinical Data

Hyo et al, 2012

Citation

Hyo Y et al. Antimicrobial effects of Burow’s solution on Staphylococcus aureus and Pseudomonas aeruginosa. Med Mol Morphol. 2012;45:66-71.

Jinnouchi et al, 2011

Citation

Jinnouchi O et al. Antimicrobial and therapeutic effects of modified Burow’s solution on refractory otorrhea. Auris Nasus Larynx. 2012;39:374-377.

Kashiwamura et al, 2004

Citation

Kashiwamura M et al. The efficacy of Burow’s solution as an ear preparation for the treatment of chronic ear infections. Otol Neurotol. 2004;25:9-13.

Clayton et al, 1990

Citation

Clayton MI et al. A double-blind, randomized, prospective trial of a topical antiseptic versus a topical antibiotic in the treatment of otorrhoea. Clin Otolaryngol Allied Sci 1990, 15, 7-10.

Lambert, 1981

Citation

Lambert IJ et al. A comparison of the treatment of otitis externa with “Otosporin” and aluminium acetate: a report from a services practice in Cyprus. J Royal Coll General Pract 1981; 31: 291-294.

Thorp et al, 1998

Citation

Thorp MA, Kruger J, Oliver S, Nilssen EL, Prescott CA. The antibacterial activity of acetic acid and Burow’s Solution as topical autological preparations. J. Laryngol. Otol. 112 (1998) 925-928.

Senska & Rusing, 2010

Citation

Senska G, Rusing D. The treatment of MRSA colonized middle ear; case report and literature review. Laryngorhinootologie. 2010; 89:404-8.

Örnhagen et al, 2013

Citation

Örnhagen H, Lundberg C, Sandelin O. External Otitis – Burow’s solution returns to favour. AllmänMedicin 2013, 2, 40-1.

Possible side effects

  • A temporary stinging sensation and/or local irritation has been reported with the use of Otinova®
  • Long-term use or overdosing may result in salt preciptations in the ear canal and dehydration of the localised area.

Safety Information

  • Not to be used by children younger than 5 years of age unbless recommended by a doctor
  • After a perforated ear drum
  • After insertion of tubes or ‘grommets’
  • If you are allergic to Aluminium Acetate
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